ISLAND Newsletter - August/September 2020 View in browser  |  Print
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A Healthy Body Is A Healthy Brain

Welcome to this edition of the ISLAND Project newsletter.  I'm Dr Jane Alty, a Senior Lecturer in Neurology at the Wicking Dementia Research and Education Centre. I am a medically qualified doctor who moved from the UK to Hobart in January 2019. I'm a member of the ISLAND study steering committee and will be the lead neurology doctor in the forthcoming ISLAND Clinic. I qualified from the University of Cambridge Medical School and undertook specialist neurology training at The National Hospital of Neurology and Neurosurgery, London, Leeds Teaching Hospitals NHS Trust, Yorkshire, and Monash Medical Centre, Melbourne. 

My main research focus is bioengineering – bringing together computer science and neurology to develop new tests that help patients, clinicians, and researchers. My research examines how movements of the body change with normal ageing and with brain disorders such as dementia, and how advanced computer science techniques can be used to develop better tests to detect early signs of dementia and Parkinson’s. Throughout my career, I have integrated research into my clinical practice. I have been the local Principal Investigator for 6 clinical trials in the UK, including complex studies examining the long-term efficacy and side effects of new Parkinson's drugs. I was awarded an MD doctorate degree by the University of York in 2014 for research into using computer science and movement sensors to measure movements more precisely in Parkinson's. This research contributed to the development of new tools and home-monitoring devices that are being used in drug trials and hospitals and have won international innovation prizes, and a new commercial company, ClearSky Medical Diagnostics.  

I now work with colleagues across the University of Tasmania, including at the Wicking Dementia Centre, School of Psychological Science and Discipline of Computer Science, to develop a new computer test called TasTest that will track movement and thinking changes in people over time. It is hoped that TasTest will help us discover new ways of detecting the earliest signs of dementia. The TasTest research study will be available to ISLAND participants in early 2021 and we hope that as many people as possible will take part. 

Risk factor - vascular health and weight
What's good for your heart is good for your brain

Vascular (heart) health is intrinsically linked to cerebrovascular (brain) health.   With each heartbeat, arteries carry between 20 to 25% of your blood to your brain, where billions of cells use about 20% of the oxygen and fuel carried in your blood.  As the brain needs a significant proportion of your blood supply to maintain normal function, looking after our blood vessels is vitally important.

Vascular health factors, including hypertension (high blood pressure) and obesity play a major role in dementia risk.  Obesity increases our risk for other chronic conditions and diseases, such as strokes and heart failure.  What we know is that people who have strokes, heart failure or heart attacks are at an increased risk of developing dementia.

The relationship between body weight and dementia is quite complicated.  As people develop dementia in older age, they tend to lost weight.  This is probably because the brain is telling them not to eat as much, but more research is needed to further examine why this happens.

At mid-life however, obesity is associated with future risk of dementia.  Additionally, people with a very large waist circumference tend to have a higher risk of dementia.  Fat deposits around the waist can be the source of inflammation and this directly affects the health of blood vessels and brain health.

You have probably heard of Vascular Dementia.  It can be caused by the accumulated effect of small and large strokes on the brain, that finally result in the degeneration of nerve cells and their connection. Vascular pathology can also increase risk of other conditions that cause dementia, such as Alzheimer’s disease.    

But for those of us who have had strokes or heart attacks, it is still not too late to make a difference to your risk of developing dementia in the future.  Researchers have found that whilst one stroke by itself may not increase the risk of dementia too much, more than one will increase risk further.  So, it’s important to work with health professionals and reduce the risk of further strokes.

The same applies to heart attacks; if you have the risk factors for heart disease, such as high blood pressure, poor diet, overweight, smoking or diabetes, managing these will reduce the risk of heart damage and failure, and also reduce the risk for dementia.

Keeping our weight within a healthy range will assist in reducing the risk of developing heart disease, strokes, hypertension and dementia.  Being physically active and having a healthy diet that's kind to your heart, arteries and blood vessels, will help maintain a healthy body weight and a healthy brain.

Modify your risk - exercise
 Alty J, Farrow M, Lawler K. Exercise and dementia prevention (2019) Image developed by O. Freeman - Wicking Dementia Research and Education Centre, Hobart.
 

Celebrate you!

According to recent statistics used by Australian Drug and Alcohol Foundation, a lot of us started drinking more than usual, and more often, over the last few months. Excessive alcohol consumption and regular binge drinking are associated with increased risk for developing dementia.  So, as restrictions slowly ease up, it’s worth taking some time to reflect.

We do not know what the upper limit is for avoiding an increase in dementia risk, so following guidelines which recommend a limit of 2 standard drinks on any day for safe alcohol consumption is advised.

Avoid having any more than 2 standard drinks on any day to lower your risk of dementia and other health conditions.

 
National Stroke Week: 31 August - 6 September What makes a good life? Lessons from the longest study on happiness

National Stroke Week: 31 August - 6 September

What makes a good life? Lessons from the longest study on happiness

The theme for this year's National Stroke week is to celebrate everyday heroes - people that know and can recognise the signs of a stroke

Become a F.A.S.T. Hero, you might possibly save a life by recognising the signs of a stroke - Face (has the face drooped?); Arms (can they lift both?); Speech (is their speech slurred and can they understand you?); Time (call 000, time is critical).

Help to raise awareness about F.A.S.T by sharing the signs of a stroke with the people in your life.

Fire In the Brain Ad-National Stroke Foundation

"What keeps us happy and healthy as we go through life? If you think it's fame and money, you're not alone – but, according to psychiatrist Robert Waldinger, you're mistaken.

As the director of a 75-year-old study on adult development, Waldinger has unprecedented access to data on true happiness and satisfaction. In this talk, he shares three important lessons learned from the study as well as some practical, old-as-the-hills wisdom on how to build a fulfilling, long life", TED.

TED-What makes a good life?
 

Not yet a member of ISLAND?

If you haven't signed up to our research programit's easy and takes just a few minutes. 

Our website, ISLAND Home, is where you will find access to our research surveys and activities.  By becoming an ISLAND member you will be kept updated with information and opportunities to help you reduce your risk of developing dementia and to be part of our combined efforts to reduce the incidence of dementia in Tasmania.

Go to our website and sign up, or if you have enrolled in any of our MOOC's, go to the log in link and sign in with your existing credentials.

ISLAND Project Partners

The University of Tasmania received funding from the Australian Government. Views and conclusions expressed in this publication are those of its authors, and may not be the same as those held by the Department of Health.

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